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***Important Announcement on COVID-19***
CHITIN is contingency planning for impediments that trial delivery teams are experiencing as a result of COVID-19.
The CHITIN Programme Management Group is giving significant consideration to the breadth of our research activities and we are liaising with the Special EU Programmes Body. Some trials have paused or put on hold elements of their work to ensure participant and researcher health & safety is prioritised.
Some trial delivery staff are working remotely and discovering new ways of working to meet research deliverables as far as possible.

We thank the CHITIN Project network for their continued dedication and commitment to the programme and we are here to support you.


BRAIN-Diabetes: Border Region Area lifestyle Intervention study for healthy Neurocognitive ageing in Diabetes (Host Organisation – QUB)

Diabetes mellitus (DM) is associated with an almost three-fold increased risk of Dementia in later life. The lag period between DM diagnosis and development of Dementia symptoms represents an opportunity for risk modification. A Scandinavian study showed that an intensive multi-domain lifestyle intervention programme (nutrition, exercise, cognitive stimulation and intensive vascular risk factor control) applied in older people (60-77 years) at higher risk for Dementia produced significant cognitive benefits after two years. 

BRAIN-Diabetes will study the feasibility and effects of a practical lifestyle intervention programme, developed in conjunction with people with DM, on cognition in older people recently diagnosed with DM living in the border areas of Ireland. 

This health research could lead to development of a practical protocol that patients can comply with which can reduce risk of cognitive decline and Dementia.

Lead Contact
Professor Peter Passmore, Queen’s University Belfast