Recognised Research Groups (RRGs) were an integral part of the HPSS R&D Strategy between 2000-2010 and accounted for a large component of the HPSS R&D Fund expenditure. The RRGs were established in the period between 2000 & 2002 with additional calls for proposals following on in 2003, 2005 & 2007. The concept was intended to facilitate focused good quality research and to create critical mass within vibrant co-operative research environments.
| RRG Theme | Title | Chief Investigator | Dates | Cost (£) |
|---|---|---|---|---|
|
Epidemiology
|
The PRIME Study extension
|
Prof Frank Kee
|
2002-2006
|
926,179
|
|
Epidemiology
|
An investigation of periodontal disease as a putative risk factor for coronary heart disease and stroke.
|
Prof Gerry Linden
|
2002-2006
|
325,381
|
|
Epidemiology
|
Genetic and Molecular Investigation of Ischaemic Heart Disease Using Family Based Studies
|
Prof Pascal McKeown
|
2002-2006
|
563,949
|
|
Child Health & Welfare
|
Nutrition, air pollution and lung disease.
|
Prof Madeleine Ennis
|
2002-2007
|
417,082
|
|
Child Health & Welfare
|
Pathophysiology of childhood asthma.
|
Dr Michael Shields
|
2002-2007
|
720,729
|
|
Child Health & Welfare
|
Long term outcome in relation to steroid use after birth in a population of very preterm children randomised to receive early or late systemic or inhaled steroids in the neonatal period.
|
Prof Henry Halliday
|
2001-2003
|
77,102
|
|
Child Health & Welfare
|
Examination of Homeobox gene expression in lung and blood cells of preterm babies.
|
Prof Henry Halliday
|
2002-2004
|
274,037
|
|
Child Health & Welfare
|
Habituation in the normal and abnormal foetus.
|
Prof Peter Hepper
|
2004-2009
|
423,416
|
|
Child Health & Welfare
|
Risk factors and protective mechanisms in Failure to Thrive in young children
|
Dr Moira Stewart
|
2003-2005
|
278,488
|
|
Child Health & Welfare
|
The psychosocial impact of facial discrepancy requiring surgical correction
|
Dr Donald Burden
|
2005-2007
|
141,412
|
|
Child Health & Welfare
|
Attitudes to breastfeeding: A health educational initiative with adolescents
|
Dr Melanie Giles
|
2005-2006
|
86,278
|
|
Child Health & Welfare
|
Can peer mentoring in first time mothers from socially deprived areas, during pregnancy and the first year of the infant’s life, have sustained effects on child growth, health and development and maternal health and well-being?
|
Prof Henry Halliday
|
2007-2009
|
234,305
|
|
Child Health & Welfare
|
Changing attitudes to breastfeeding: The evaluation of an evidence based intervention with adolescents in Northern Ireland
|
Dr Melanie Giles
|
2007-2010
|
327,616
|
|
Child Health & Welfare
|
A longitudinal investigation of teasing/bullying among children with cleft lip and/or palate
|
Dr Donald Burden
|
2007-2010
|
357,909
|
|
Vision
|
To evaluate the impact of visual impairment and a variety of rehabilitation strategies on visually impaired adults and children in Northern Ireland.
|
Prof Jonathan Jackson
|
2002-2009
|
407,148
|
|
Vision
|
The study of inherited ophthalmic disorders.
|
Miss Giuliana Silvestri
|
2002-2007
|
483,594
|
|
Vision
|
An investigation of the cellular and molecular mechanisms leading to vascular cell dysfunction during diabetic retinopathy
|
Prof Alan Stitt
|
2002-2007
|
160,223
|
|
Vision
|
Advanced lipoxidation end-products and the pathogenesis of diabetic retinopathy
|
Dr Tim Curtis
|
2005-2007
|
168,298
|
|
Vision
|
Is age-related macular degeneration less common in light-protected populations?
|
Dr Giuliana Silvestri
|
2007-2010
|
319,333
|
|
Vision
|
Genetic and phenotypic characterisation of retinal dystrophy patients in NI
|
Dr David AC Simpson
|
2007-2011
|
475,647
|
|
Vision
|
Molecular dissection of sporadic and familial keratoconus in Northern Ireland
|
Dr Colin E Willoughby
|
2007-2010
|
435,168
|
|
Diabetes, Endocrinology & Nutrition
|
Inadequate sperm: a molecular biological investigation of the commonest endocrine disorder.
|
Prof Sheena Lewis
|
2001-2004
|
149,876
|
|
Diabetes, Endocrinology & Nutrition
|
Pathophysiology and clinical relevance of insulin action in hypertension, diabetes and pituitary disease.
|
Dr Brew Atkinson
|
2001-2006
|
544,985
|
|
Diabetes, Endocrinology & Nutrition
|
Diabetes, obesity, intrauterine growth and atherosclerosis: the fetal origins hypotheses.
|
Dr David R McCance
|
2001-2009
|
702,475
|
|
Diabetes, Endocrinology & Nutrition
|
The use of stable long-acting analogues of GIP and GLP-1 for diabetes therapy.
|
Dr Patrick Harriet
|
2002-2005
|
130,530
|
|
Diabetes, Endocrinology & Nutrition
|
Non-invasive determination of vascular impedance properties of the ocular circulation in vivo
|
Prof Gary McVeigh
|
2002-2005
|
281,278
|
|
Diabetes, Endocrinology & Nutrition
|
Developing evidence-based practice in diabetes care
|
Prof Vivien Coates
|
2002-2006
|
110,434
|
|
Diabetes, Endocrinology & Nutrition
|
Vascular complications of diabetes mellitus: cellular pathophysiology.
|
Prof Elizabeth Trimble
|
2002-2007
|
392,856
|
|
Diabetes, Endocrinology & Nutrition
|
Mapping of genetic susceptibility genes for nephropathy and albuminuria employing novel family studies in type 2 diabetes
|
Dr Christopher Patterson
|
2002-2007
|
183,998
|
|
Diabetes, Endocrinology & Nutrition
|
Identification of the Genetic Predisposition to Diabetic Nephropathy.
|
Prof Peter Maxwell
|
2003-2007
|
527,886
|
|
Diabetes, Endocrinology & Nutrition
|
A genome wide search for susceptibility genes for nephropathy and albuminuria employing novel family studies in type 2 diabetes.
|
Dr Damian Fogarty
|
2003-2007
|
309,021
|
|
Diabetes, Endocrinology & Nutrition
|
The genetic basis of hyperlipidaemia and vascular disease in Northern Ireland
|
Dr Colin Graham
|
2003-2008
|
574,563
|
|
Diabetes, Endocrinology & Nutrition
|
Diabetes proteomics, pancreatic beta cell targets and drug discovery.
|
Prof Peter Flatt
|
2003-2008
|
207,288
|
|
Diabetes, Endocrinology & Nutrition
|
Effects of Omega-3 Fatty Acids on Platelet and Vascular reactivity in patients with type 2 diabetes mellitus and hypertension
|
Prof Dennis Johnston
|
2004-2007
|
243,387
|
|
Diabetes, Endocrinology & Nutrition
|
Production and secretion of glycated forms of intestinal GLP-1 and GIP: Involvement in hormonal control of glucose metabolism and diabetes
|
Dr Aine Marie McKillop
|
2005-2007
|
131,015
|
|
Diabetes, Endocrinology & Nutrition
|
A longitudinal of periodontal disease as a putative risk factor for coronary heart disease and stroke
|
Prof Gerard Linden
|
2007-2013
|
402,244
|
|
Diabetes, Endocrinology & Nutrition
|
Genetic association analyses of functional candidate genes for diabetic nephropathy identified by a genome-wide microsatellite screen
|
Dr David Savage
|
2007-2009
|
213,701
|
|
Diabetes, Endocrinology & Nutrition
|
Pathophysiology of insulin resistance and insulin secretion defects and the development and progression of diabetes: influence on diet and autoimmunity
|
Dr Steven J Hunter
|
2007-2010
|
504,901
|
|
Diabetes, Endocrinology & Nutrition
|
Doppler ultrasound investigations of ocular and skeletal microcirculations in Type 1 Diabetes Mellitus
|
Prof Gary McVeigh
|
2007-2011
|
459,528
|
|
Diabetes, Endocrinology & Nutrition
|
Studies of the prevalence and determinants of obesity and cardiovascular risk in young children: The HAPO Family Study
|
Dr David R McCance
|
2007-2012
|
679,151
|
|
Diabetes, Endocrinology & Nutrition
|
An investigation into the modulation of obesity-associated monocyte/macrophage function, vascular inflammation and insulin resistance by PPAR agonist treatment
|
Dr Lesley Powell
|
2007-2010
|
353,931
|
|
Diabetes, Endocrinology & Nutrition
|
Insulin action and vascular risk: influence of endocrine replacement and antihypertensive therapies
|
Prof Patrick M Bell
|
2008-2011
|
441,669
|
|
Cancer
|
Characterisation of a novel candidate ovarian tumour suppressor gene. |
Dr Hilary Russell
|
2002-2007
|
453,306
|
|
Cancer
|
Enhancement of anti-tumour efficacy by targeting tumour-specific micro-environmental factors.
|
Prof David Hirst
|
2002-2007
|
205,071
|
|
Cancer
|
Further characterisation of a novel gene, DIR1, and other stress response genes with a potential role in radio and chemosensitivity.
|
Dr Tracy Robson
|
2002-2007
|
217,540
|
|
Cancer
|
Discovery of potential novel anti-cancer drugs derived from natural products and by rational design.
|
Dr Hendrik van den Berg
|
2002-2007
|
222,974
|
|
Cancer
|
Epigenetic gene silencing in cancer.
|
Dr Colum Walsh
|
2002-2007
|
233,814
|
|
Cancer
|
Late cell cycle checkpoints in cancer.
|
Prof Stephen Downes
|
2003-2008
|
239,855
|
|
Cancer
|
Functional analysis of the BRCA1 tumour suppressor gene in response to DNA damage and cytotoxic stress.
|
Prof Paul Harkin
|
2001-2006
|
350,423
|
|
Cancer
|
The pathogenesis and treatment of anaemia in cancer.
|
Prof Terry Lappin
|
2002-2005
|
283,434
|
|
Cancer
|
Characterisation and clinical significance of TS regulated signalling pathways
|
Prof Patrick Johnston
|
2001-2006
|
429,808
|
|
Cancer
|
Evaluation of biological activity of faecal water as biomarker for colon cancer risk
|
Prof Ian Rowland
|
2001-2004
|
118,031
|
|
Cancer
|
Folate status and carcinogenesis
|
Dr Helene McNulty
|
2002-2004
|
116,596
|
|
Cancer
|
The role of machine vision and computerised expert systems in the diagnosis and prognosis of cancer.
|
Prof Peter Hamilton
|
2002-2007
|
130,057
|
|
Cancer
|
Pathways of inflammation associated oncogenesis of the colon
|
Prof Frederick Campbell
|
2002-2006
|
358,885
|
|
Cancer
|
Genetic screening in breast and breast/ovarian cancer families
|
Dr Anthony Bjourson
|
2004-2007
|
192,621
|
|
Cancer
|
The validation and integration of (18FDG) PET-CT functional data into the radiotherapy treatment planning process for non-small cell lung cancer
|
Dr Alan Robert Hounsell
|
2005-2008
|
267,762
|
|
Cancer
|
Oesophageal adenocarcinoma in Barrett’s oesophagus: contribution of the Northern Ireland Barrett’s Register and mathematical modelling
|
Dr Brian Johnston
|
2005-2008
|
166,304
|
|
Cancer
|
Long term follow-up of middle-aged men with elevated prostatic specific antigen levels: a population based study
|
Dr Anna Gavin
|
2005-2007
|
201,389
|
|
Cancer
|
The role the insulin growth factor axis and folate metabolism in the oesophageal inflammation, metaplasoa, adenocarcinoma sequence
|
Dr Liam Murray
|
2007-2009
|
219,282
|
|
Cancer
|
Expression profiling of circulating colorectal cancer (CRC) epithelial cells: Clinical Relevance
|
Prof Patrick Johnston
|
2007-2012
|
905,949
|
|
Cancer
|
To develop and validate a test for the diagnosis and prediction of response to therapy in the BRCA1 deficient/basal sub type of breast cancer
|
Prof Paul Harkin
|
2007-2012
|
941,275
|
|
Cancer
|
Clonal methylation profiling of morphologically normal mucosa as a risk marker of colitis-associated colorectal neoplasia (CACRN)
|
Prof Frederick Campbell
|
2007-2011
|
369,555
|
|
Trauma & Rehabilitation
|
Autologous cultured osteoblasts in the treatment of delayed fracture union
|
Dr Canice McGivern
|
2003-2007
|
571,091
|
|
Trauma & Rehabilitation
|
Cerebral palsy population-based survey
|
Mr Aidan Cosgrove
|
2003-2008
|
478,564
|
|
Trauma & Rehabilitation
|
Arthritis: Joint Destruction Vs Joint Repair
|
Dr Madeleine Rooney
|
2003-2009
|
586,688
|
|
Trauma & Rehabilitation
|
Phenytoin in the treatment of chronic wounds
|
Mrs Julia Shaw
|
2004-2008
|
248,379
|
|
Trauma & Rehabilitation
|
Preferential wound healing in the oral mucosa
|
Prof Chris Irwin
|
2003-2005
|
156,236
|
|
Trauma & Rehabilitation
|
The assessment of imaging performance of X-ray Imaging Systems using both practical and computer modelling approaches applied to clinical situations
|
Dr Kieran Cranley
|
2003-2007
|
220,346
|
|
Trauma & Rehabilitation
|
Real and Virtual 3D Environments
|
Dr John Winder
|
2003-2005
|
130,725
|
|
Trauma & Rehabilitation
|
A comparison of Bobath therapy and gait-specific training in acute stroke: a randomised controlled trial
|
Dr Sheila Lennon
|
2005-2007
|
83,083
|
|
Trauma & Rehabilitation
|
Treatment of shoulder pain by injection and physiotherapy
|
Dr Ian Ryans
|
2008-2012
|
266,157
|
|
Trauma & Rehabilitation
|
The identification of infection and proteomic biomarkers in the progression of juvenile and adult arthritis
|
Dr Madeleine Rooney
|
2007-2010
|
325,945
|
|
Trauma & Rehabilitation
|
Drug delivery to open wounds using novel semi-solid devices as an augmentative strategy for laceration repair
|
Dr Mark Jenkins
|
2007-2011
|
723,698
|
|
Trauma & Rehabilitation
|
Predicting poor hand functional outcome in Rheumatoid Arthritis – a comparison of high-resolution ultrasound examination and occupational therapy clinical hand assessment
|
Dr Aubrey Bell
|
2008-2015
|
291,008
|
|
Trauma & Rehabilitation
|
Group Exercise Therapy for Mobility and Balance in People with Multiple Sclerosis (MS): a Randomised Controlled Trial
|
Dr Andrea Lowe-Strong
|
2008-2012
|
428,563
|
|
Trauma & Rehabilitation
|
Exercise and auricular electroacupuncture: a subject-and assessor-blind feasibility randomised controlled trial of the effectiveness of a combined approach for chronic low back pain
|
Prof Suzanne McDonough
|
2007-2009
|
174,094
|
|
Infectious Diseases
|
Improvement of prosthetic joint infection diagnosis and treatment
|
Dr Sheila Patrick
|
2003-2008
|
360,142
|
|
Infectious Diseases
|
Molecular pharmacology of cell surface g-protein coupled receptors for Interleukin-8
|
Dr David Waugh
|
2003-2009
|
304,747
|
|
Infectious Diseases
|
Molecular Determinants of Morbillivirus Pathogenesis
|
Prof Louise Cosby
|
2004-2009
|
301,570
|
|
Infectious Diseases
|
Identification and characterisation of Toll-like receptors involved in the response to oral Microbes
|
Prof James Johnston
|
2004-2007
|
302,718
|
|
Infectious Diseases
|
Coxiella burnetii infection in Northern Ireland: Epidemiology & Diagnosis
|
Dr Conall McCaughey
|
2004-2007
|
447,228
|
|
Infectious Diseases
|
The development, dissemination and significance of antibiotic resistance within the human food chain
|
Prof David McDowell
|
2004-2008
|
547,200
|
|
Infectious Diseases
|
Development and clinical validation of a respiratory microarray to study the clinical significance of concurrent infections of the respiratory tract
|
Dr Peter Coyle
|
2005-2008
|
364,234
|
|
Infectious Diseases
|
Characterisation of in vitro and in vivo rhamnolipid production by opportunistic Pseudomonas aeruginosa isolated from cystic fibrosis patients: a chemical analysis and functional genomic approach
|
Dr James Dooley
|
2005-2009
|
314,234
|
|
Infectious Diseases
|
A study to compare the efficacy of two potential diagnostic assays: A Fluorescein conjugated monoclonal antibody in vivo assay and nested real time PCR assay to rapidly and accurately diagnose herpes simplex keratitis
|
Dr Tara McMullan
|
2005-2009
|
205,716
|
|
Infectious Diseases
|
Generation of a genetic signature of severe RSV disease – an important step towards maximising efficiency of Palivizumab (Synagis) prescription
|
Dr Ultan Power
|
2007-2012
|
947,577
|
|
Infectious Diseases
|
Skin bacteria as a source of surgical infections: molecular Epidemiology and prevention in wound contamination
|
Dr Sheila Patrick
|
2008-2015
|
857,674
|
|
Neuroscience & Mental Health
|
The role of a-synuclein in relation to Parkinson's disease and Dementia with Lewy Bodies
|
Dr Andrew Wallace
|
2003-2005
|
94,413
|
|
Neuroscience & Mental Health
|
Processing of precursor proteins implicated in Alzheimer’s Disease, Parkinson’s Disease, and Dementia with Lewy Bodies
|
Dr Brent Irvine
|
2003-2008
|
533,954
|
|
Neuroscience & Mental Health
|
The role of the prefrontal serotonin system in cognition/Brain SPECT Imaging in Psychiatry
|
Prof David King
|
2002-2008
|
817,257
|
|
Neuroscience & Mental Health
|
The Genetic Epidemiology of Tardive Dyskinesia in Northern Ireland
|
Dr Tony O’Neill
|
2003-2006
|
275,511
|
|
Neuroscience & Mental Health
|
The Northern Ireland First Episode Psychosis Outcome Study
|
Dr Teresa Rushe
|
2003-2008
|
835,210
|
|
Neuroscience & Mental Health
|
The application of systematic proteomics to characterise the neuroretina and the inherent subsistence factors that maintain its integrity
|
Dr Jim Curray
|
2003-2005
|
172,627
|
|
Neuroscience & Mental Health
|
Bioinformatic and experimental characterisation of retinal-specific gene expression
|
Dr David Simpson
|
2003-2005
|
245,655
|
|
Neuroscience & Mental Health
|
Determination of platelet BACE activity in Alzheimer’s disease patients and its relationship to genetic variation at the BACE locus
|
Dr Peter A Passmore
|
2004-2006
|
251,832
|
|
Neuroscience & Mental Health
|
A study of motor function and dopamine transporter and receptor status in Parkinson and Parkinson plus syndromes using infra-red oculography, radionucline and MRI imaging
|
Dr J Mark Gibson
|
2005-2009
|
319,883
|
|
Neuroscience & Mental Health
|
The genetic Epidemiology of MS in Northern Ireland
|
Dr Colin Graham
|
2002-2007
|
403,718
|
|
Neuroscience & Mental Health
|
Individual and family differences in Mental Health: An Epidemiological Study
|
Prof Brendan Bunting
|
2003-2007
|
1,021,967
|
|
Neuroscience & Mental Health
|
The development and evaluation of a mobile phone-based streaming (MPVS) system in providing home-suport for patients with Alzheimer’s disease
|
Dr David Craig
|
2007-2010
|
262,457
|