The national contract value review (NCVR) is a standardised, national approach to costing for commercial contract research
From 14 October 2024, NCVR will include Early Phase (phase I and IIa) and Advanced Therapeutic Medicinal Products (ATMPs) studies.
Since its introduction across the UK in 2023 it has helped speed up commercial research set up times, making the UK a more attractive place for commercial organisations to undertake research studies, ensuring UK patients have earlier access to new treatments.
The NCVR focuses on agreeing the resources and price needed to set up commercial research studies within the HSC/NHS. This work forms part of a broader common goal to ensure clinical research continues to thrive in Northern Ireland, and across the UK, for the benefit of patients and the public.
National contract value review is a UK wide programme
There is reciprocal recognition of contract value reviews conducted by NHS organisations across the UK. In Northern Ireland the HSC R&D Approvals Service oversee NCVR working closely with other nations and NIHR. For queries relating to NCVR Northern Ireland, please contact ncvr@hscni.net. For queries relating to the other UK nations, you should refer to the information provided for England, for Wales, and Scotland.
Early impact of the national contract value review
The NCVR process has contributed to a reduction in the time taken to set up commercial research studies by 36% (12 month analysis). In addition to faster set up, NCVR has freed up resource at sites to carry out other research activity.
Sponsor requirements
- To submit your study for the national contract value review you will need to access the interactive Costing Tool (iCT); the National Institute for Health and Care Research (NIHR) provides guidance on using the interactive Costing Tool, and how the tool calculates the cost of studies at sites
- Include the appropriate new UK template agreement, with the new financial appendix, in your Integrated Research Applications System (IRAS) submission. Do not use any previous agreements for any IRAS submission on or after 1st October
- Copy the iCT finance schedule, when available, into the financial appendix of the agreement to share with sites
- Complete the site iCT process, before sharing the locked-down site-level iCT with the site inside the Central Portfolio Management System (CPMS). This should be done at the same time as sharing the completed contract template with the site, to support site invoicing and internal disbursement
Supporting documents
- The iCT Study Resource Review SOP (including ATMPs/Early Phase) defines the process capturing the National Study Resource Requirements within the Interactive Costing Tool prior to the creation of site specific versions for participating sites.
- The NCVR ATMP and Early Phase Costing Guidance assists with completion of the interactive Costing Tool (iCT).
- The NCVR Lead Site Review Checklist supports national reviewers in conducting a thorough study resource review and contains key items to consider.
- For assistance with queries relating to model template agreements in Northern Ireland please contact ResearchContracts@innovations.hscni.net